You may have better luck asking your question in the F150 group.
Could be that your lock motors are just getting tired. The sable my son is driving has 1 lock that acts like what your describing. Pain to get to, so I've never really tried to change it. I did spray it with some lithium grease and it help for a short while.
1969 ForDor Thunderbird
2006 Dodge Charger (wifes car)
2000 Ranger Regular cab
2.5L with A/C backed up by the 5 speed manual, 2WD.
159,000+ on the clock.
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