Ok here you go. If the 250 spears are the same. These will be your measurements.
From the back of the hood to the first hole I have 6 11/16 and it is 2 1/4 up from the lower lip on the hood.
The second hole in from the back of the hood is 14 1/8 and is 2 1/8 up from the bottom lip of the hood.
The last hole out is 21 5/16 from back of the hood and 2 up from the lower hood lip. All holes appear to be 1/4 in in diameter. Again these are for a F250 hood spear if the 100s are the same then you are good to go.