Ethanol is corrosive and at levels much over 10% will start eating away at your fuel system. Flex fuel vehicles have fuel system components that are designed to cope with the ethanol as well as you need to increase the injector pulse and move the timing to get the same power output from e85 as you do Gasoline. E85 has a much lower BTU output so it takes a lot more e85 to be injected into the cylinders.
This is why if you look at a window sticker of a flex fuel vehicle, the miles per tank is considerably lower on e85.
Short answer, NO
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